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Enoyl coenzyme A hydratase 1 Enoyl coenzyme A hydratase 1, as the key enzyme in the second step of mitochondrial fatty acid -oxidation, has the capacity to regulate a variety of pathophysiological processes, including conferring protection against metabolic disorders and obesity (143)

Fifthly, cereblon E3 ligase is expressed in multiple tissues, enabling cereblon-based PROTACs to treat various diseases 62

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5,6 Translation of these observations into human trials is limited by variable SCOBY composition, complex metabolites, unverified historical claims, as well as small, self-reported, and single-product trials